14 days in North Carolina Itinerary

Created using Klarna Trips North Carolina trip itinerary maker
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Drive
1
Highlands
— 3 nights
Drive
2
Asheville
— 4 nights
Drive
3
Raleigh
— 3 nights
Drive
4
Manteo, Roanoke Island
— 2 nights
Drive

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Highlands — 3 nights

Step off the beaten path and head to Dry Falls and Glen Falls. Escape the urban bustle at Cullasaja Falls and Yonah Mountain Campground. Explore the numerous day-trip ideas around Highlands: 12 Spies Vineyards and Farm (in Rabun Gap), Hemlock Falls Trail (in Clarkesville) and Old Sautee Store (in Sautee Nacoochee).

To find reviews, photos, where to stay, and more tourist information, read our Highlands trip itinerary planning website.

Saint Louis to Highlands is an approximately 11-hour car ride. You can also fly; or drive; or do a combination of bus and taxi. The time zone difference when traveling from Saint Louis to Highlands is 1 hour. Traveling from Saint Louis in September, you will find days in Highlands are slightly colder (79°F), and nights are about the same (57°F). Finish up your sightseeing early on the 20th (Tue) so you can go by car to Asheville.
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Parks · Nature · Outdoors · Trails
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Find places to stay Sep 17 — 20:

Asheville — 4 nights

Land of the Sky

You'll discover tucked-away gems like Pisgah National Forest and Max Patch. Next up on the itinerary: surround yourself with nature on Tumblestone Tours and Transportation, view the masterpieces at Colin's Creatures, relax and rejuvenate at some of the best spas, and learn the secrets of beer at BREW-ed.

To see other places to visit, where to stay, maps, and tourist information, refer to the Asheville road trip site.

You can drive from Highlands to Asheville in 2 hours. Alternatively, you can drive. Expect a daytime high around 79°F in September, and nighttime lows around 59°F. Wrap up your sightseeing on the 24th (Sat) early enough to drive to Raleigh.
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Find places to stay Sep 20 — 24:

Raleigh — 3 nights

City of Oaks

You'll explore the less-touristy side of things at JC Raulston Arboretum at NC State University and North Carolina Museum of Natural Sciences. Escape the urban bustle at Neuse River Trail and House Creek Greenway Trail. Change things up with these side-trips from Raleigh: Carolina Tiger Rescue (in Pittsboro) and American Tobacco Trail (in Apex). There's lots more to do: stroll around Pullen Park, whizz through the canopy at some of the top local zipline courses and adventure parks, pause for some serene contemplation at Holy Name of Jesus Cathedral, and stop by Videri Chocolate Factory.

To see where to stay, more things to do, ratings, and other tourist information, read Raleigh trip itinerary builder tool.

Drive from Asheville to Raleigh in 4.5 hours. Alternatively, you can drive; or fly; or take a bus. In September in Raleigh, expect temperatures between 82°F during the day and 63°F at night. Wrap up your sightseeing on the 27th (Tue) early enough to drive to Manteo.
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Find places to stay Sep 24 — 27:

Manteo, Roanoke Island — 2 nights

Kick off your visit on the 28th (Wed): visit a coastal fixture at Bodie Island Lighthouse, then enjoy the sand and surf at Pea Island National Wildlife Refuge, and then get a taste of the local shopping with Kitty Hawk Kites - Nags Head. Keep things going the next day: head outdoors with Outdoor Activities and then look for all kinds of wild species at Alligator River National Wildlife Refuge.

For other places to visit, maps, where to stay, and tourist information, refer to the Manteo route app.

Traveling by car from Raleigh to Manteo takes 3.5 hours. Alternatively, you can drive; or do a combination of train, bus, and car; or do a combination of flight and car. September in Manteo sees daily highs of 79°F and lows of 68°F at night. Wrap up your sightseeing on the 29th (Thu) early enough to travel back home.
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Find places to stay Sep 27 — 29:

North Carolina travel guide

4.5
The Tar Heel State
A top destination for a holiday in nature, North Carolina provides a seemingly endless variety of outdoor activities, including hiking, mountain climbing, and skiing. While the state's rural regions offer a taste of traditional Appalachian music and culture, its increasingly diverse big cities feature modern skyscrapers, renowned museums, and historical neighborhoods perfect for sightseeing tours. The coastal region, famous for its year-round temperate climate, attracts millions of annual visitors, making North Carolina the sixth most-visited state in the country. Though it's hard to find a quiet time of year in coastal North Carolina, the state's inland areas retain many secluded corners where you can experience the laid-back Old South atmosphere.
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