21 days in Argentina, Oruro & Villazon Itinerary

Created using Klarna Trips South America Trip Planner
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Drive
1
Oruro, Bolivia
— 1 night
Fly to Tarija, Bus to Villazon
2
Villazon, Bolivia
— 1 night
Drive
3
Humahuaca, Argentina
— 2 nights
Drive
4
Iruya, Argentina
— 1 night
Drive
5
Humahuaca, Argentina
— 1 night
Drive
6
Tilcara, Argentina
— 2 nights
Drive
7
Purmamarca, Argentina
— 1 night
Drive
8
San Salvador de Jujuy, Argentina
— 1 night
Drive
9
Salta, Argentina
— 1 night
Drive
10
San Antonio de los Cobres, Argentina
— 1 day
Drive
11
Salta, Argentina
— 2 nights
Drive
12
Cachi, Argentina
— 1 night
Drive
13
Cafayate, Argentina
— 3 nights
Drive
14
Salta, Argentina
— 1 night
Fly

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Oruro, Bolivia — 1 night

Kick off your visit on the 19th (Sat): learn more about the world around you at Archaeological Museum, take in the architecture and atmosphere at Catedral de Oruro, then make a trip to Plaza 10 de Febrero, then contemplate in the serene atmosphere at Sanctuary of El Socavon, and finally make a trip to Las Mina de San Jose.

To see more things to do, other places to visit, reviews, and tourist information, read our Oruro trip planner.

Buenos Aires, Argentina to Oruro is an approximately 29-hour car ride. The time zone changes from Argentina Standard Time (ART) to Bolivia Time (BOT), which is usually a -1 hour difference. While traveling from Buenos Aires, expect a bit cooler days and much colder nights in Oruro, ranging from highs of 24°C to lows of 3°C. Finish up your sightseeing early on the 20th (Sun) so you can travel to Villazon.
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Historic Sites · Museums
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Villazon, Bolivia — 1 night

Kick off your visit on the 20th (Sun): pause for some photo ops at Plazoleta Simon Bolivar and then stroll around Plaza Libertad.

For more things to do, photos, maps, and tourist information, read Villazon tour itinerary planning tool.

Getting from Oruro to Villazon by combination of flight and bus takes about 9.5 hours. Other options: drive; or take a bus. You will leave for Humahuaca on the 21st (Mon).
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Parks
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Humahuaca, Argentina — 2 nights

Kick off your visit on the 21st (Mon): pause for some serene contemplation at Iglesia San Francisco de Paula and then explore the striking landscape at Quebrada de Humahuaca. Get ready for a full day of sightseeing on the next day: examine the collection at Museo Folklorico Regional, admire the striking features of Cabildo de Humahuaca, then appreciate the history behind Monumento a los Heroes de la Independencia, and finally see the interesting displays at Estudio Museo Ramoneda.

To see more things to do, photos, maps, and tourist information, you can read our Humahuaca online day trip planner.

Getting from Villazon to Humahuaca by car takes about 2.5 hours. Due to the time zone difference, you'll lose 1 hour traveling from Villazon to Humahuaca. You will leave for Iruya on the 23rd (Wed).
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Side Trip
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Iruya, Argentina — 1 night

Kick off your visit on the 23rd (Wed): don't miss a visit to Plaza Sargento Rosa Guevara, then take some stellar pictures from Mirador de la Cruz, then pause for some serene contemplation at Iglesia Nuestra Senora del Rosario y San Roque, and finally take some stellar pictures from Mirador El Condor.

To find other places to visit, reviews, ratings, and more tourist information, use the Iruya trip itinerary planner.

Drive from Humahuaca to Iruya in 2.5 hours. Wrap up your sightseeing by early afternoon on the 24th (Thu) to allow enough time to drive to Humahuaca.
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Historic Sites
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Humahuaca, Argentina — 1 night

For where to stay, more things to do, photos, and other tourist information, refer to the Humahuaca online itinerary maker.

Getting from Iruya to Humahuaca by car takes about 2.5 hours. Finish your sightseeing early on the 25th (Fri) to allow enough time to drive to Tilcara.
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Side Trip
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Tilcara, Argentina — 2 nights

On the 26th (Sat), look for gifts at EL MOLLE Fabrica de Alfajores, don't miss a visit to Punto y Coma Libros Cafe Musica, examine the collection at Museo Posta de Los Hornillos, explore the fascinating underground world of Cuevas de Waira, then take in the dramatic natural features at Las Paletas Del Pintor, and finally explore the different monuments and memorials at Cementerio Nuestra Senora del Carmen. Get ready for a full day of sightseeing on the 27th (Sun): admire the masterpieces at Museo Regional de Pintura Jose A Terry, examine the collection at Museo Arqueologico Dr. Eduardo Casanova, don't miss a visit to Dripping, take in the dramatic scenery at Waterfall Garganta Del Diablo, then don't miss a visit to Plaza Alvarez Prado, and finally make a trip to Pucara de Juella.

To find photos, ratings, maps, and tourist information, use the Tilcara trip maker website.

You can drive from Humahuaca to Tilcara in an hour. Another option is to take a bus. On the 28th (Mon), you'll travel to Purmamarca.
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Purmamarca, Argentina — 1 night

Start off your visit on the 28th (Mon): contemplate in the serene atmosphere at Iglesia de Santa Rosa de Lima, then make a trip to Plaza 9 de Julio, and then take in the awesome beauty at The Hill of Seven Colors.

For ratings, photos, and other tourist information, refer to the Purmamarca trip maker app.

Purmamarca is just a stone's throw from Tilcara. Wrap up your sightseeing on the 29th (Tue) to allow time to drive to San Salvador de Jujuy.
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Parks · Nature · Outdoors · Trails
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San Salvador de Jujuy, Argentina — 1 night

On the 30th (Wed), admire the landmark architecture of Cabildo De Jujuy, get engrossed in the history at Museo Historico J.G. Lavalle, make a trip to Plaza Belgrano, don't miss a visit to Casa de Gobierno de Jujuy, then pause for some serene contemplation at Iglesia de San Francisco y Museo de Arte Sacro, and finally pause for some serene contemplation at Catedral de San Salvador de Jujuy.

To see maps, ratings, photos, and other tourist information, go to the San Salvador de Jujuy road trip planning website.

You can drive from Purmamarca to San Salvador de Jujuy in 1.5 hours. In November, daily temperatures in San Salvador de Jujuy can reach 34°C, while at night they dip to 19°C. Finish up your sightseeing early on the 30th (Wed) so you can go by car to Salta.
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Museums · Historic Sites
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Salta, Argentina — 1 night

Salta the Beautiful

Start off your visit on the 1st (Thu): hunt for treasures at Mercado Artesanal Tradicional, contemplate the waterfront views at Dique Cabra Corral, pause for some serene contemplation at Iglesia Nuestra Senora de La Candelaria de La Vina, take in the spiritual surroundings of Basilica Menor San Francisco, then examine the collection at Museo Casa de Leguizamon, and finally don't miss a visit to Calle Balcarce.

To find where to stay, maps, traveler tips, and more tourist information, go to the Salta driving holiday planner.

You can drive from San Salvador de Jujuy to Salta in 2.5 hours. Expect a daytime high around 33°C in December, and nighttime lows around 19°C. Finish your sightseeing early on the 2nd (Fri) to allow enough time to drive to San Antonio de los Cobres.
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Parks · Nature · Historic Sites · Museums
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San Antonio de los Cobres, Argentina — 1 day

On the 2nd (Fri), don't miss a visit to Viaducto de la polvorilla and then take in the architecture and atmosphere at La Iglesia de San Antonio de Padua.

Discover how to plan a San Antonio de los Cobres trip in just a few steps with Klarna Trips's itinerary builder.

You can drive from Salta to San Antonio de los Cobres in 3 hours. You'll have a few hours on the 2nd (Fri) to wrap things up before traveling to Salta.
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Historic Sites
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Salta, Argentina — 2 nights

Salta the Beautiful

Start off your visit on the 2nd (Fri): pause for some photo ops at Monumento General Martín Miguel de Güemes, examine the collection at Museo Casa de Leguizamon, and then don't miss a visit to Calle Balcarce.

Klarna Trips's itinerary builder makes planning a Salta trip simple and quick.

Traveling by car from San Antonio de los Cobres to Salta takes 3 hours. Wrap up your sightseeing on the 4th (Sun) to allow time to drive to Cachi.
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Historic Sites · Parks · Nature · Museums
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Cachi, Argentina — 1 night

Start off your visit on the 4th (Sun): explore the ancient world of Parque Nacional Los Cardones, then make a trip to Cachi, and then examine the collection at Museo Arqueologico Pio Pablo Diaz.

To see more things to do, photos, maps, and tourist information, use the Cachi road trip website.

Traveling by car from Salta to Cachi takes 3.5 hours. Alternatively, you can take a bus. Wrap up your sightseeing by early afternoon on the 5th (Mon) to allow enough time to drive to Cafayate.
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Parks · Nature · Historic Sites · Wineries
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Cafayate, Argentina — 3 nights

Tuscany of Argentina

Start off your visit on the 5th (Mon): stop by Carmela y Oliverio and then see the interesting displays at Museo Regional y Arqueologico Rodolfo Bravo. Here are some ideas for day two: tee off at La Estancia De Cafayate, take in the dramatic scenery at Cascadas del Rio Colorado, explore the striking landscape at El Anfiteatro, explore the striking landscape at Garganta del Diablo Salta, then identify plant and animal life at Quebrada del Rio de las Conchas, and finally make a trip to Plaza Central.

For ratings, photos, more things to do, and more tourist information, go to the Cafayate trip builder app.

Drive from Cachi to Cafayate in 4 hours. Alternatively, you can do a combination of taxi and bus; or take a bus. Finish up your sightseeing early on the 8th (Thu) so you can go by car to Salta.
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Parks · Wineries · Nature · Outdoors
Side Trip
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Salta, Argentina — 1 night

Salta the Beautiful

Kick off your visit on the 8th (Thu): browse the eclectic array of goods at Mercado Artesanal Tradicional, explore the activities along Dique Cabra Corral, make a trip to Iglesia Nuestra Senora de La Candelaria de La Vina, take in the spiritual surroundings of Basilica Menor San Francisco, then examine the collection at Museo Casa de Leguizamon, and finally don't miss a visit to Calle Balcarce.

To find photos, other places to visit, traveler tips, and more tourist information, use the Salta trip planning tool.

Drive from Cafayate to Salta in 3 hours. Alternatively, you can take a bus. On the 9th (Fri), wrap the sightseeing up by early afternoon so you can fly back home.
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Historic Sites · Parks · Nature · Museums
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Argentina travel guide

4.4
Landmarks · Bodies of Water · Specialty Museums
Land of Contrasts
Home to the highest and lowest points in South America, diverse Argentina enthralls visitors with its contrasting landscapes and rich cultural heritage. A tour of Argentina reveals a sprawling land of fiercely proud and hardworking gauchos, the legendary cowboys of South America's pampas. A vacation in Argentina also leads you to giant urban centers, filled with modern tourist attractions that include fine restaurants, award-winning museums, and renowned public parks, gardens, and zoos. Away from big cities, Argentina sightseeing combines visits to mighty waterfalls situated inside World Heritage-listed national parks in the north of the country, with excursions to icy glaciers in the south.
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Province of Salta travel guide

4.5
Sacred & Religious Sites · Natural History Museums · Landmarks