21 days in Uruguay & Paraguay Itinerary

Created using Klarna Trips South America route planner
Make it your trip
Fly to Carrasco International /General C L Berisso Airport, Drive to Punta del Este
Punta del Este, Uruguay
— 3 nights
Montevideo, Uruguay
— 5 nights
Colonia del Sacramento, Uruguay
— 3 nights
Bus to Puerto Madero, Taxi to El Palomar, Fly to Iguazu, Drive to Ciudad Del Este
Ciudad Del Este, Paraguay
— 3 nights
Bus to Ypacaraí, Taxi to Asuncion
Asuncion, Paraguay
— 4 nights


Punta del Este, Uruguay — 3 nights

Monaco of South America

With plenty of modern casinos, well-developed beaches, chic restaurants, and upscale hotels, Punta del Este vacations draw visitors from Argentina, Brazil, and beyond.
Get out of town with these interesting Punta del Este side-trips: Playa Punta Ballena (in Punta Ballena), Piriapolis (Castillo de Piria & Cerro San Antonio) and Pan De Azucar (in Pan de Azucar). There's still lots to do: admire the masterpieces at Museo – Taller de Casapueblo, kick back and relax at Playa Brava, don't miss a visit to Puerto de Punta del Este, and head outdoors with MAREAS Escuela de Buceo.

To see more things to do, photos, reviews, and tourist information, you can read our Punta del Este trip maker tool.

Groningen, The Netherlands to Punta del Este is an approximately 30-hour combination of flight and car. The time zone difference when traveling from Groningen to Punta del Este is minus 4 hours. Traveling from Groningen in April, expect nights in Punta del Este to be much hotter, around 19°C, while days are somewhat warmer, around 24°C. Wrap up your sightseeing on the 6th (Thu) early enough to drive to Montevideo.
Outdoors · Museums · Parks · Beaches
Side Trips
Find places to stay Apr 3 — 6:

Montevideo, Uruguay — 5 nights

With a rich cultural scene and plenty of developed beaches, Montevideo vacations appeal to a growing number of visitors from around the world.
Get out of town with these interesting Montevideo side-trips: Pizzorno Family Estates (in Canelones) and Bodegas Castillo Viejo (in Las Piedras). There's much more to do: make a trip to Plaza Independencia, admire the striking features of Palacio Salvo, get a sense of history and politics at Palacio Legislativo, and admire the masterpieces at Palacio Taranco.

Start your trip to Montevideo by creating a personalized itinerary on Klarna Trips.

Getting from Punta del Este to Montevideo by car takes about 2 hours. Other options: take a bus. Plan for slightly colder nights when traveling from Punta del Este in April since evenings lows in Montevideo dip to 16°C. Finish up your sightseeing early on the 11th (Tue) so you can go by car to Colonia del Sacramento.
Museums · Shopping · Neighborhoods · Wineries
Side Trips
Find places to stay Apr 6 — 11:

Colonia del Sacramento, Uruguay — 3 nights

Sleepy cobbled streets lined with pastel-colored houses lead down to the water in Colonia del Sacramento.
You'll find plenty of places to visit near Colonia del Sacramento: Carmelo (Bodega Campo Tinto, Bodega Boutique El Legado, &more). There's much more to do: appreciate the extensive heritage of Barrio Historico, stop by Almacen La Carlota, don't miss a visit to Bastion de San Pedro, and contemplate the waterfront views at Rio de la Plata.

To find reviews and more tourist information, read our Colonia del Sacramento route tool.

You can drive from Montevideo to Colonia del Sacramento in 2.5 hours. Another option is to take a bus. In April in Colonia del Sacramento, expect temperatures between 26°C during the day and 17°C at night. Finish your sightseeing early on the 14th (Fri) so you can travel to Ciudad Del Este.
Wineries · Historic Sites · Museums · Nature
Side Trip
Find places to stay Apr 11 — 14:

Ciudad Del Este, Paraguay — 3 nights

Supermarket of South America

The commercial center of eastern Paraguay, busy Ciudad Del Este serves primarily as a shopping destination for Argentines and Brazilians.
Step out of Ciudad Del Este with an excursion to Refugio Tati Yupi in Hernandarias--about 42 minutes away. There's much more to do: take in the dramatic scenery at Saltos del Monday, head outdoors with Snow Park, buy something for everyone on your list at SAX, and pause for some photo ops at Scientific Monument Moises Santiago Bertoni.

To find ratings, traveler tips, photos, and other tourist information, read Ciudad Del Este online day trip planner.

Traveling by combination of bus, taxi, flight, and car from Colonia del Sacramento to Ciudad Del Este takes 7.5 hours. Alternatively, you can do a combination of ferry, bus, flight, and car; or drive. While traveling from Colonia del Sacramento, expect a bit warmer days and about the same nights in Ciudad Del Este, ranging from highs of 32°C to lows of 20°C. Wrap up your sightseeing on the 17th (Mon) to allow time to travel to Asuncion.
Parks · Nature · Shopping · Wildlife
Side Trips
Find places to stay Apr 14 — 17:

Asuncion, Paraguay — 4 nights

Mother of Cities

Paraguay's capital and economic center, Asuncion ranks among the youngest cities on the continent, with more than half of its residents under 30 years of age.
Venture out of the city with trips to San Bernardino (Lago Ypacarai & Aventura Xtrema). There's much more to do: steep yourself in history at Casa de la Independencia, hunt for treasures at Mercado La Recova, take in nature's colorful creations at Botanical Garden and Zoo (Jardin Botanico y Zoologico), and ponder the world of politics at Palacio de López.

For traveler tips, maps, reviews, and tourist information, read Asuncion road trip planning site.

Do a combination of bus and taxi from Ciudad Del Este to Asuncion in 4.5 hours. Alternatively, you can drive; or take a bus. Due to the time zone difference, you'll gain 1 hour traveling from Ciudad Del Este to Asuncion. In April in Asuncion, expect temperatures between 34°C during the day and 22°C at night. Wrap up your sightseeing by early afternoon on the 21st (Fri) to allow time for travel back home.
Parks · Museums · Nature · Tours
Side Trips
Find places to stay Apr 17 — 21:

Uruguay travel guide

Landmarks · Scenic Walking Areas · Art Museums
Switzerland of South America
One of the smallest countries in South America, tourist-friendly Uruguay is often called the "Switzerland of South America" because of its consistent economic development and progressive society. Open-minded Montevideo serves as the starting point of most Uruguay vacations, offering visitors an eclectic cultural scene and a chance to discover some of South America's major architectural treasures. Away from the cosmopolitan capital city, vacations in Uruguay involve exploring wildlife-rich areas along the Atlantic and touring the rustic interior on horseback, gaucho style. In this sports-loving country, the highlight of your Uruguay trip might just be a soccer match between Penarol and Nacional, the country's two major clubs.

Paraguay travel guide

Heart of South America
Divided in half by its eponymous river, Paraguay is a land of contrasts, especially between its lush eastern region where most of the population lives and the arid west, filled with rustic villages and old Jesuit colonies. Although under Spanish rule for three centuries and with a recent history of dictatorships and wars, Paraguay retained its native Guarani culture, with more than 80 percent of population of indigenous heritage. You'll find plenty of things to do in Paraguay, from touring cosmopolitan cities and quaint Jesuit colonies, to browsing affordable arts and crafts stores and sailing on rivers that crisscross the diverse natural landscape that makes up this landlocked nation.