22 days in Los Angeles, San Francisco & Las Vegas Itinerary

Surrounded by mountain ranges, forests, valleys, beaches, and deserts, the metropolitan area of Los Angeles is home to over 17 million people.

The Huntington Library, Art Museum and Botanical Gardens and Santa Monica Pier will appeal to history buffs. Satisfy your inner culture vulture at Ronald Reagan Presidential Library and Museum and Mission San Juan Capistrano. Get out of town with these interesting Los Angeles side-trips: Third Street Promenade (in Santa Monica), Manhattan Beach (in Manhattan Beach) and Crystal Cove (in Laguna Beach). Pack the 24th (Fri) with family-friendly diversions at Disneyland Park. There's still lots to do: immerse yourself in nature at Santa Monica State Beach, examine the collection at Madame Tussauds Hollywood, make a trip to The Wizarding World of Harry Potter, and admire the landmark architecture of Walt Disney Concert Hall.

To see other places to visit, more things to do, maps, and other tourist information, you can read our Los Angeles trip builder.

Use the Route module to find suitable travel options from your home destination to Los Angeles. In March, plan for daily highs up to 74°F, and evening lows to 54°F. Finish up your sightseeing early on the 24th (Fri) so you can catch the flight to San Francisco.

San Francisco is a top holiday destination featuring scenic beauty and great ethnic and cultural diversity.

Get a sense of the local culture at Alcatraz Island and Crocker Art Museum. Kids will appreciate attractions like Golden Gate Bridge and California State Capitol Museum. Get out of town with these interesting San Francisco side-trips: Sacramento (Old Sacramento & California State Railroad Museum). The adventure continues: examine the collection at de Young Museum, admire the masterpieces at Asian Art Museum, get curious at California Academy of Sciences, and take in the spiritual surroundings of Grace Cathedral.

To find ratings, more things to do, and tourist information, use the San Francisco journey website.

Fly from Los Angeles to San Francisco in 3 hours. Alternatively, you can drive; or take a bus. When traveling from Los Angeles in March, plan for slightly colder days and about the same nights in San Francisco: temperatures range from 65°F by day to 50°F at night. Finish your sightseeing early on the 1st (Sat) to allow enough time to fly to Las Vegas.

Nicknamed the "Entertainment Capital of the World," Las Vegas sits in the middle of a desert in the southern section of Nevada.

Satisfy your inner culture vulture at The Strip and The LINQ Promenade. Museum-lovers will appreciate Wayne Newton's Casa de Shenandoah and Shelby American Inc. Next up on the itinerary: indulge in some culinary diversions at a local gastronomic tour, join the crowd at Las Vegas Motor Speedway, examine the collection at The Mob Museum, and buy something for everyone on your list at Downtown Container Park.

To find traveler tips, more things to do, ratings, and more tourist information, read our Las Vegas trip planner.

Traveling by flight from San Francisco to Las Vegas takes 3 hours. Alternatively, you can drive; or do a combination of subway, train, and bus. In April, Las Vegas is a bit warmer than San Francisco - with highs of 80°F and lows of 57°F. Wrap up your sightseeing on the 8th (Sat) early enough to fly back home.