7 days in Saint Louis, Birmingham & Perdido Key Itinerary

Test the local claim that Saint Louis is second only to Washington, D.C. in the number of free activities available by spending your holiday exploring the city's central neighborhoods, famous for their restored century-old red-brick buildings.

Saint Louis is known for sightseeing, museums, and zoos & aquariums. Your trip includes some of its best attractions: pause for some serene contemplation at Cathedral Basilica of Saint Louis, appreciate the history behind The Gateway Arch, admire the natural beauty at Missouri Botanical Garden, and admire the masterpieces at Saint Louis Art Museum.

To find reviews, other places to visit, photos, and more tourist information, read Saint Louis travel itinerary planner.

New York City to Saint Louis is an approximately 4-hour flight. You can also drive; or take a bus. The time zone difference when traveling from New York City to Saint Louis is minus 1 hour. Traveling from New York City in May, you will find days in Saint Louis are a bit warmer (77°F), and nights are about the same (57°F). Finish your sightseeing early on the 20th (Sat) to allow enough time to fly to Birmingham.

Birmingham may be one of America's most controversial cities.

On the 21st (Sun), take in nature's colorful creations at Birmingham Botanical Gardens, then stroll through Rotary Trail, then get engrossed in the history at Birmingham Civil Rights Institute, and finally stroll around Kelly Ingram Park. On the 22nd (Mon), you'll have a packed day of sightseeing: don't miss a visit to Alabama Veterans Memorial Park, then bet on your favorite at Barber Vintage Motorsports Museum, then take in the spiritual surroundings of 16th Street Baptist Church, and finally stroll through Vulcan Park and Museum.

To find photos, maps, reviews, and tourist information, read our Birmingham tour itinerary maker tool.

Fly from Saint Louis to Birmingham in 5.5 hours. Alternatively, you can drive; or take a bus. In May, plan for daily highs up to 81°F, and evening lows to 60°F. Finish up your sightseeing early on the 22nd (Mon) so you can go by car to Perdido Key.

Perdido Key, Florida is an unincorporated community in Escambia County, Florida, United States, between Pensacola and Orange Beach, Alabama. Kick off your visit on the 23rd (Tue): play a few rounds at Lost Key Golf Club, then stop by Perdido Key Seafood, then take a tour by water with Boat Tours & Water Sports, and finally tee off at Perdido Bay Golf Club.

To see maps, traveler tips, where to stay, and more tourist information, read our Perdido Key trip planning site.

Traveling by car from Birmingham to Perdido Key takes 4.5 hours. In May, daily temperatures in Perdido Key can reach 82°F, while at night they dip to 65°F. Finish up your sightseeing early on the 24th (Wed) so you can go by car back home.